Products

Etrebelle PN

Introducing the hybrid PLA + PN regenerative implant, the Etrebelle PN! It stimulates collagen production and gives the skin a revitalizing glow due to the combination of PLA and PN, forming a powerful blend of a soft tissue injectable implant. Etrebelle PN is available in 436.8 mg per vial in every package.

Etrebelle PNPLA + PN

BR Pharm Co., Ltd.

Product Description

The two most potent ingredients for skin aesthetics, PN (polynucleotide) and PLA (polylactic acid), are formulated in the Etrebelle PN solution, a hybrid collagen skin booster. When these two components are combined, their effects on skin renewal and collagen stimulation are amplified, producing outstanding results. While the PN ingredient concentrates on enhancing inflammatory characteristics within, the PLA component is in charge of the injectable volume restoration. the skin. As a result, Etrebelle PN modulates the foreign body response and promotes cell proliferation, thus proving its safety and effectiveness.

Additionally, Etrebelle PN provides fundamental improvement from physical recovery to collagen production and tissue regeneration. It also improves skin elasticity, restoring the compounds elastin and collagen fibers for firmer and more youthful skin texture and overall health. The manufacturer, BR Pharm Co., Ltd., has also infused hyaluronic acid (HA) into the injectable to produce moisturizing effects and deep hydration. When HA, PLA, and PN are combined, they create a synergistic effect that allows Etrebelle PN to provide a number of advantages, including collagen stimulation, the promotion of growth factor secretion to aid in skin tissue repair, and the restoration of physical volume in specific areas.

Active ingredient

PLA 150mg + PN 35mg + HA 15mg

Target area

Deep wrinkles & volume restoration

Sessions

3-4 sessions every 4-6 weeks

Duration

Up to 24 months

Strengths of Etrebelle PN

Revitalizes the quality of the skin by encouraging collagen stimulation and physical volume restoration.
Improving sagging skin by encouraging collagen and elastin regeneration, which thickens and strengthens the dermal layers.
An injectable soft tissue implant that combines the potent effects of PN, HA, and PLA.
It is safe to inject into the body because it is made entirely of biodegradable ingredients.
Etrebelle PN has proven its safety and effectiveness in anti-inflammatory properties and regenerative effects
Reduces fine wrinkles and lines and other signs of aging
Reduces inflammatory effects by activating essential growth factors to defend the skin cells from further damage.
The structure of PLLA particles from the emulsification technique of the product prevents nodule formation or cannula clogging.

Scope of Application

Signs of aging
Hollow cheeks and volume loss
Dry and rough skin texture
Inflamed skin, especially from the cellular level
Sagging skin
Damaged skin tissue
Decreasing levels of collagen and elastin fibers

Product Composition

There are two primary components, including another one that enhances the effects of Etrebelle PN: PLA, PN, and HA

Polylactic acid (PLA)

Polylactic acid, or PLA, is a biodegradable, biocompatible polymer that supports the skin's natural production of new collagen. PLA, with its sponge-like (porous) foamy particle network structure, is present in Etrebelle PN per vial.

Polynucleotide (PN)

Polynucleotide, or PN, inhibits the inflammatory cytokine initially and promotes cell proliferation by activating essential growth factors. It also restores the skin's health and vitality, as well as enhancing the effects of PLA.

Hyaluronic acid (HA)

Because HA (hyaluronic acid) is a naturally occurring polymer polysaccharide that is frequently found in the human body, dermal fillers containing HA are typically biocompatible with the body. Etrebelle is made of highly cross-linked hyaluronic acid with minimal assistance from cross-linkers.

Duration of Effect

After injection with Etrebelle PN, it can produce volume restoration and hydration and improve inflammatory effects. After a month, the HA material will have to naturally degrade; PLA particles then take position, resulting in the initial volumizing effects, while PN particles initiate the activation of essential growth factors and stimulate fibroblasts.

Then, after 6 months, the PLA particles will have to integrate within the skin tissue structure, inducing collagen stimulation. Finally, after a year, the collagen fibers will now enrich both the extracellular components and the skin tissue environment. Overall, Etrebelle PN can last for up to 24 months, especially when regular treatment sessions are done.

Etrebelle PN Product Information

Packaging1 x 436.8 mg per vial
Composition150mg PLA + 35 mg PN + 15 mg Hyaluronic acid (HA)
PLA Particle Size30~50 µm
Method of AdministrationMid- to deep-dermis layer
Cannula size27G-32G
ReconstitutionMix 6 mL of sterile distilled water and 1 mL of lidocaine for over 30 minutes.
Recommended dosageIt is recommended to give about 1 to 2 vials per session
Treatment intervalReceive about 3 to 4 treatment sessions for about 4 to 6 weeks
Duration of effectUp to 24 months
StorageStore in a cool, dry place and at room temperature. Keep away from direct sunlight.
Shelf life48 months from manufacturing date
ManufacturerBR Pharm Co., Ltd.

Etrebelle PN must be used only by medical professionals and trained aestheticians to prevent adverse reactions and achieve optimal results.